Episode 6: Why Chronic Pain Persists: Zombie Cells and the Missing Lymphatic Link
Part of The Lymph-Brain Revolution Podcast with
John Ossipinsky (LymphMan)
Published on: January 7, 2026Â
Season: 1 Episode:Â 6
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Episode Summary
Chronic pain affects millions of people, yet many are told that nothing is wrong. In this episode, John Ossipinsky (LymphMan) explains why chronic pain often persists long after tissues should have healed — and why relief requires more than symptom management.
New research shows chronic pain is closely linked to inflammation, trapped cellular waste, and aging “zombie” cells. When the lymphatic system becomes overwhelmed and can’t properly clear waste from tissues, pain and tightness can linger. This episode explores why chronic pain is often a clearance issue, not just a nerve issue, and how supporting lymphatic flow may help reduce and control long-term pain.
Key takeaways from this episode:
- Chronic pain often persists because inflammation and cellular waste are not being cleared from tissue
- Pain is not always caused by nerve damage or structural injury
- Aging “zombie” cells can amplify inflammation and pain signals
- Pain is closely linked to anxiety, depression, and nervous system stress
- Trauma, surgery, and inactivity can overwhelm the lymphatic system
- Supporting lymphatic flow helps create the conditions needed for pain relief
In This Episode, You’ll Learn
- Why chronic pain often continues long after tissues should have healed
- Why medications may dull symptoms but don’t resolve the root cause of pain
- How inflammation, cellular waste, and aging “zombie” cells contribute to persistent pain
- Why chronic pain affects women more frequently and more intensely
- The connection between chronic pain, anxiety, and depression
- Why chronic pain is often a clearance issue — not just a nerve issue
- How supporting lymphatic flow can help reduce and control long-term pain
Timestamps
00:00 Intro & Welcome
01:10 Episode Summary
02:00 Why Chronic Pain Persists
06:00 Why Chronic Pain Doesn’t Go Away
14:00 Why Chronic Pain Affects Women More
22:00 Zombie Cells, Inflammation & Pain
31:00 The Lymphatic System & Pain Relief
39:00 ⚡ Actionable Tips
44:30 Closing & Call to Action
Studies Mentioned
- Worldwide study finds high rates of depression and anxiety in people with chronic pain (2025)
- Drugs targeting 'zombie cells' show promise for treating chronic back pain (2025)
- Could marijuana be an effective pain alternative to prescription medications? (2019)
- A healthy diet helps the weighty battle with chronic pain (2024)
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Together, we’re changing the world’s health — one lymphatic system at a time.
 Keep Flowing 💚 — @LymphMan
The information shared on this podcast and website is for educational and informational purposes only and is not intended as medical advice. It is not a substitute for professional medical diagnosis, treatment, or care. Always consult your physician or qualified healthcare provider regarding any medical condition or health concern.